Integrative Genome-wide Analysis Reveals Cooperative Regulation of Alternative Splicing by hnRNP Proteins
نویسندگان
چکیده
منابع مشابه
Terrae Incognitae: Integrative Genomic Analysis of Hnrnp L Splicing Regulation
Alternative splicing is a critical component of human gene control that generates functional diversity from a limited genome. Defects in alternative splicing are associated with disease in humans. Alternative splicing is regulated developmentally and physiologically by the combinatorial actions of cisand trans-acting factors, including RNA binding proteins that regulate splicing through sequenc...
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ژورنال
عنوان ژورنال: Cell Reports
سال: 2012
ISSN: 2211-1247
DOI: 10.1016/j.celrep.2012.02.001